Publication of the 2025 Annual Report of the Federal Select Agent Program

Today, the Federal Select Agent Program (FSAP) is pleased to announce the publication of its eleventh annual report of aggregate program data, the 2025 Annual Report of the Federal Select Agent Program. The report summarizes data for calendar year 2025.

The report provides the American public with insight into the regulatory activities of the program. The report summarizes both the regulatory functions of FSAP, as well as compliance with the select agent and toxin regulations at laboratories across the Nation. The report also highlights how recent changes to the list of regulated select agents and toxins impacted program data across the board.

The report summarizes aggregate program data in areas such as:

  • Numbers and types of registered entities, as well as amendments to registrations
  • Most frequently registered select agents or toxins
  • Security risk assessments performed
  • Number of inspections conducted
  • Key observations related to inspection findings and compliance with the select agent and toxin regulations
  • Reported thefts, losses, and releases of select agents or toxins
  • Identifications and transfers of select agents or toxins
  • Publications and outreach activities

As in previous years, data from this year’s report underscore that overall, entities registered with the program are compliant with the regulations, and none of the small number of reported incidents during the year resulted in a significant risk to public health or agriculture. 

The full report, an infographic summarizing the key findings, and past reports are all available online on the Federal Select Agent Program website.  

For more than two decades, FSAP has provided critical leadership and oversight in the areas of biosafety and security. With the oversight provided by FSAP during this time, laboratories have been able to continue to work with dangerous biological agents and toxins in a safe and secure manner.

If you have any questions about the report, please contact APHIS/DASAT at 301-851-2070 or dasat@usda.gov, or CDC/DRSC at 404-718-2000 or LRSAT@CDC.gov.

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